Loading...

29 posters, 13 topics, 90 authors, 29 institutions

ePostersLive by SciGen Technologies S.A. All rights reserved.

86

Evaluating the Radiological Reporting and Subsequent Clinical Management of Incidental Coronary Artery Calcification (CAC) in Primary CT Skeletal Surveys (pCTSS) for Patients with Suspected Multiple Myeloma (MM) in a Large Teaching Hospital

Part of Topic

Chest

Radiological Reporting and Subsequent Clinical Management of Incidental Coronary Artery Calcification in CT Skeletal Surveys for Patients with Suspected or Confirmed Myeloma in a Large Teaching Hospital

Firnaaz Mohideen 1, Faris Khan 1, Holly Christopher 1, Marusa Kotnik 1, Teo Wetscherek 1, Veronika Sadler 1, Faisal Basheer 2, Timothy Sadler 1

[1] Department of Radiology, Addenbrooke’s Hospital, Cambridge, UK

[2] Department of Haematology, Addenbrooke’s Hospital, Cambridge, UK

BACKGROUND & OBJECTIVES

Coronary artery calcification (CAC) is an established imaging marker of coronary artery disease[1], but incidental detection on non-cardiac CT is frequently under-recognised, under-reported, and under-managed.
 
Patients with myeloma face a greater overall cardiovascular risk due to both disease-related (e.g. inflammation, paraproteinaemia) and treatment-related (e.g. corticosteroids, chemotherapy) factors.[2]
 
CT skeletal surveys (CTSS), routinely used for bone evaluation in suspected myeloma, offer a valuable opportunity for early identification of CAC and initiation of preventative interventions in this high cardiovascular risk population.
 
We conducted two audits in parallel to evaluate standards of (1) reporting and (2) subsequent clinical management of incidental CAC on CTSS, followed by a repeat cycle for each audit to assess improvement post-intervention.

STANDARDS & TARGETS

While there are no CTSS-specific national guidelines, recommendations from the British Societies of Cardiovascular Imaging (BSCI), Cardiac CT (BSCCT), and Thoracic Imaging (BSTI) offer advice on reporting/management of incidental CAC on non-gated thoracic CT.[3] Our audits used the following standards derived from their consensus:

1. Reporting & Grading

If CAC is explicitly identified, it should be quantified using a simple visual scale (none, mild, moderate, severe) unless there is a   valid reason making this difficult or inappropriate (e.g. previous CABG, stent in situ).

→ target: 100%

2. Suggesting Recommendations in Report

If CAC is explicitly identified, simple recommendations for further assessment or management should be provided in the report text   itself.

→ target: 100%

3. Enacting Subsequent Clinical Management

If CAC is explicitly identified, some form of appropriate clinical management (e.g. patient discussion, lifestyle modification, statin   initiation, GP referral, etc.) should be enacted by the primary medical team responsible for the patient’s care.

→ target: 100%

METHODOLOGY

INTERVENTIONS

INTERVENTIONS TO IMPROVE REPORTING:

- educational presentation of findings: to specialty leads for oncological imaging to reinforce value of looking at coronary arteries on all CTSS

- guidance to radiologists: if a grade cannot be given where calcification is present, include an explicit reason in the report for why not (e.g. previous CABG, stent in situ)

INTERVENTIONS TO IMPROVE MANAGEMENT:

- educational presentation of findings: to both specialty leads for oncological imaging and haematology consultants specialising in myeloma to raise awareness

- guidance to radiologists: introduction of a standardised reporting template for CAC, which automatically includes simple recommendations for further management in the report text if CAC is explicitly identified

- guidance to clinicians: clinicians receiving a report definitively identifying CAC advised to…

> suggest lifestyle changes to minimise overall cardiovascular risk

> initiate/optimise statin therapy for primary prevention

> encourage patient to discuss long-term cardiovascular risk reduction with GP

- patient information sheet: co-developed with haematology consultants specialising in myeloma to empower patients with information needed to discuss strategies for cardiovascular risk reduction in primary care

RESULTS

1. In reports in which the coronary arteries were/CAC was explicitly commented on, what degree of calcification was noted?

2. What percentage of reports in which the coronary arteries were/CAC was explicitly commented on visually-qualified the   severity of calcification OR had an appropriate reason not to comment?

3. In reports where CAC was definitively identified, was there any simple recommendation re. further assessment/management   given in the report text?

4. In the most at-risk patients (i.e. those with risk factors for CVD) in whom CAC was definitively identified in the report and were   not already on/on sub-optimal primary prevention, was any subsequent clinical management enacted?

DISCUSSION & CONCLUSION

Sub-optimal reporting of incidental CAC directly translates into sub-optimal management of CAC-positive patients, with only 7% of high-risk individuals receiving any intervention at initial haematology follow-up prior to our changes being implemented.
 
Following implementation of changes, both of our audits demonstrated clear improvements from both reporting and management perspectives.
 
Raising awareness among relevant specialties, embedding simple management recommendations within the radiology report, and prompting clinicians to enact simple management all proved effective in positively changing clinical practice.
 
Implementing management (e.g. lifestyle modification, statin initiation, etc.) at the time of myeloma diagnosis has the potential to significantly reduce long-term cardiovascular morbidity and mortality in this high-risk group, improving overall health outcomes beyond their haematological condition alone.

REFERENCES

[1] Beverly, J., & Budoff, M. J. (2020). Use of Coronary Computed Tomography for Calcium Screening of Atherosclerosis. Heart international, 14(2), 76–79. https://doi.org/10.17925/HI.2020.14.2.76

[2] El-Cheikh, J., Moukalled, N., Malard, F., Bazarbachi, A., & Mohty, M. (2023). Cardiac toxicities in multiple myeloma: an updated and a deeper look into the effect of different medications and novel therapies. Blood cancer journal, 13(1), 83. https://doi.org/10.1038/s41408-023-00849-z

[3] Williams, M. C., Abbas, A., Tirr, E., Alam, S., Nicol, E., Shambrook, J., Schmitt, M., Hughes, G. M., Stirrup, J., Holloway, B., Gopalan, D., Deshpande, A., Weir-McCall, J., Agrawal, B., Rodrigues, J. C. L., Brady, A. J. B., Roditi, G., Robinson, G., & Bull, R. (2021). Reporting incidental coronary, aortic valve and cardiac calcification on non-gated thoracic computed tomography, a consensus statement from the BSCI/BSCCT and BSTI. The British journal of radiology, 94(1117), 20200894. https://doi.org/10.1259/bjr.20200894

cr2025 banner
Copyright © 2015-2026, ePostersLive® SciGen is a registered trademark of SciGen Technologies S.A. Patent pending.

This website and third-party tools we use rely on cookies for the best user experience. By selecting "I agree", you agree to cookie usage as described in our Privacy Policy.