Time From Collagenase Injection To Manipulation Does Not Affect Outcomes In Dupuytren's Disease

Elijah G. Bingham, BS1, Purushottam Nagarkar, MD2, Nirbhay S. Jain, MD1, Meaghan L. Barr, MD2, Cathy Tang, MD3, Dong Lee, BS4, Irene Chang, BS5, Michael Delong, MD1, Prosper Benhaim, MD4

Introduction

• Dupuytren’s disease is a relatively common condition encountered by hand surgeons. Injection of collagenase Clostridium histolyticum enzyme, followed by manual manipulation, is effective in managing Dupuytren’s disease.

• For a variety of reasons, patients are often unable to return to clinic for manipulation within the recommended 24-72 hours from injection.

• Therefore, we sought to study the impact of time from collagenase injection to manipulation on outcomes and post-procedure complications.