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Oral versus Intravenous Acetaminophen for Post-­Tonsillectomy Pain in Children
Thurs, April 6, 8:15-9:45 am
Salon 5

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Oral versus intravenous acetaminophen for post-tonsillectomy pain in children


Tonsillectomy with or without adenoidectomy is a common surgical procedure in children and can result in significant post-operative pain.  Acetaminophen has been shown to be effective in reducing pain and post-operative opioid requirements, and multiple dosing routes are available.

Several studies have demonstrated an opioid sparing effect and improvement of pain control with intravenous (IV) acetaminophen vs. placebo and/or active controls (meperidine, rectal acetaminophen, tramadol).  Although pharmacokinetic data suggests superiority for the IV route, no clinical studies have compared oral versus IV acetaminophen for post-tonsillectomy pain control in children.

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