Intravenous acetaminophen use associated with reduced odds of 30-day readmission after total knee arthroplasty
•Inverse probability of treatment (propensity score) weighted regression was performed to assess the association between IV APAP and 30-day readmission
In adjusted model, risk of 30-day readmission was 71% less likely in the IV APAP than the PO APAP cohort (OR 0.29, 95% CI 0.23 to 0.35; p<0.001)
Nationwide utilization of IV APAP in TKA may potentially result in $260 million in savings/year
Lower 30-day readmission rates in IV cohort when compared to other studies
Reduced 30-day readmission rates in TKA patients who received IV vs. PO APAP
Overall lower 30-day readmission rates when compared to literature
Potential to save $260 million if implemented nationwide
Valuable information for orthopaedic surgeons and healthcare administrators
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