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INFLUENZA A (H1N1) INFECTION AND COMPLICATED CASES Antonopoulou Eleni, Lefa Polykseni, Papadaki Ergani Paediatric Department, Thriasion General Hospital , Athens, Greece Introduction: The new Influenza A virus infection (H1N1) was defined as pandemic by WHO in June 2009. The disease could be severe if bacterial infection is implicated, when occurs with pneumonia which leads to respiratory or polyorganic deficiency, or connected with aggravation of a system disease. Purpose: The purpose of this study is to describe the incidences of hospitalized children with H1N1 and the frequency of complicated cases. Material-Methods: We study retrospectively all the patients with H1N1 during November 2009-February 2009. The virus detected in nasopharyngeal speciments and confirmed by RT- PCR. Results: 45 children were enrolled to our study. 16 (35.6%) were males and 29 (64.4%) were females aged from 1 month to 14 years old. All children had high fever and clinical respiratory symptoms, and 9/45 (20%) gastrointestinal. Risk factors (bronchial asthma) for severe disease reported to 6/45 (13.3%) cases. The chest X-Ray showed pneumonia in 5/45 (11%) bronchoalveolitis in 2/45 (4.44%) and peribronchial percolations 6/45 (13.3%). They also presented 1/45 afebrile seizures, 1/45 bacillemia (Haemophilus Influenza non-type b in a patient aged 1 month old), 1/45 myositis , 4/45 streptococcus tonsillitis, 3/45 acute medius otitis. The infection H1N1 is associated with neutropenia in percentage 8.88%. We administered oseltamivir in 2 cases. The average time of hospitalization was 4.2 days. Conclusions: Severe disease occurred frequently with pneumonia (15.5%). None incident was transported in Intensive Care Unit. All our patients had a good outcome.

PULMONOLOGY