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Thermo-Expandable Ureteral Metal Stent (MemokathTM051) for the treatment of UPJ obstruction. Is it safe?

Wednesday, 8 June, 2011 - 11:08
Board 1

Thermo-Expandable Ureteral Metal Stent (MemokathTM051) for the treatment of UPJ obstruction. Is it safe? Introduction:   The MemokathTM051 (PNN Medical, Denmark), which is a thermo-expandable ureteral metal stent, is designed to be permanent in situ. Several studies showed that this stent provides effective and durable drainage of chronic ureteral strictures without the high rate of side-effects of JJ-stenting. The standard treatment of uretero-pelvic junction obstruction (UPJO) is usually considered to be laparoscopic pyeloplasty, but in some cases this it is not possible and other options are desirable. The aim of the present study was to evaluate drainage and safety aspects of long-term use of the MemokathTM051-stent in the treatment of  UPJO.   Materials and Methods: 12 patients (5 F, 7 M) with UPJO from 5 Danish centres were included. A total of 14 stents were used. Mean age of the patients was 52 years. The follow-up included KUB and renography.   Results:   The insertion of the Memokath was easy and without complications. The average follow-up of the patients was 9 months. The average indwelling time of an individual Memokath was 7,7 months (range 8 days - 64 months). 10 stents migrated after a short period of time (7 distally and 3 proximally). In 7 cases the patients had pain due to the stent. After stent removal 10 patients needed further treatment of the obstruction. In the remaining two cases the UPJ stricture obviously was relieved after stent removal and they remained without symptoms and with stable split function on renography.   Conclusions:   Because of the high rate of complications (migration and pain) the MemokathTM051-stent does not seem to be suitable for the of UPJ strictures.  

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